BDBM50504432 CHEMBL4571862

SMILES Fc1ccc2[nH]cc(C3CC(=O)N(CCCCN4CCC(CC4)c4c[nH]c5ccccc45)C3=O)c2c1

InChI Key InChIKey=GNSLKVMRVNNRSW-UHFFFAOYSA-N

Data  6 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 50504432   

Target5-hydroxytryptamine receptor 1A(Human)
Medical University of Warsaw

Curated by ChEMBL
LigandPNGBDBM50504432(CHEMBL4571862)
Affinity DataKi:  13nMAssay Description:Displacement of [3H]-8-OH-DPAT from human 5HT1A receptor expressed in CHO-K1 cell membranes incubated for 60 mins by microbeta scintillation counting...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/18/2021
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 6(Human)
Medical University of Warsaw

Curated by ChEMBL
LigandPNGBDBM50504432(CHEMBL4571862)
Affinity DataKi:  29nMAssay Description:Displacement of [3H]-LSD from human 5-HT6 receptor expressed in HEK293 cells incubated for 1 hr by liquid scintillation counting methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/18/2021
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 2A(Human)
Medical University of Warsaw

Curated by ChEMBL
LigandPNGBDBM50504432(CHEMBL4571862)
Affinity DataKi:  50nMAssay Description:Displacement of [3H]-Ketanserin from human 5-HT2A receptor expressed in rat cortex tissue incubated for 30 mins by liquid scintillation counting meth...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/18/2021
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 7(Human)
Medical University of Warsaw

Curated by ChEMBL
LigandPNGBDBM50504432(CHEMBL4571862)
Affinity DataKi:  50nMAssay Description:Displacement of [3H]-5-CT from human 5HT7 receptor expressed in HEK293 cells incubated for 1 hr by liquid scintillation counting methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/18/2021
Entry Details Article
PubMed
TargetSodium-dependent serotonin transporter(Human)
Medical University of Warsaw

Curated by ChEMBL
LigandPNGBDBM50504432(CHEMBL4571862)
Affinity DataKi:  51nMAssay Description:Displacement of [3H]-imipramine from human serotonin transporter expressed in HEK293 cells membranes incubated for 30 mins by microbeta scintillation...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/18/2021
Entry Details Article
PubMed
TargetD(2) dopamine receptor(Human)
Medical University of Warsaw

Curated by ChEMBL
LigandPNGBDBM50504432(CHEMBL4571862)
Affinity DataKi:  190nMAssay Description:Displacement of [3H]-raclopride from human D2L receptor expressed in HEK293 cells incubated for 1 hr by liquid scintillation counting methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/18/2021
Entry Details Article
PubMed