BDBM50504347 CHEMBL365781

SMILES CC(SC1=CC(=O)c2ccccc2C1=O)C(O)=O

InChI Key InChIKey=OUFIZXDVAUZHEC-UHFFFAOYSA-N

Data  5 IC50  1 Kd

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 50504347   

TargetM-phase inducer phosphatase 1(Human)
Montana State University

Curated by ChEMBL
LigandPNGBDBM50504347(CHEMBL365781)
Affinity DataIC50: 5.40E+3nMAssay Description:Inhibition of recombinant Cdc25A (unknown origin) using OMFP as substrate measured every 30 sec for 10 mins by fluorometric assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/18/2021
Entry Details Article
PubMed
TargetM-phase inducer phosphatase 2(Human)
Montana State University

Curated by ChEMBL
LigandPNGBDBM50504347(CHEMBL365781)
Affinity DataIC50: 5.20E+3nMAssay Description:Inhibition of recombinant Cdc25B (unknown origin) using OMFP as substrate measured every 30 sec for 10 mins by fluorometric assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/18/2021
Entry Details Article
PubMed
TargetDual specificity mitogen-activated protein kinase kinase 7(Human)
Montana State University

Curated by ChEMBL
LigandPNGBDBM50504347(CHEMBL365781)
Affinity DataKd:  2.10E+3nMAssay Description:Binding affinity to MKK7 (unknown origin) expressed in HEK293 cells assessed as dissociation constant by kinomescan methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/18/2021
Entry Details Article
PubMed
TargetNeutrophil elastase(Human)
Montana State University

Curated by ChEMBL
LigandPNGBDBM50504347(CHEMBL365781)
Affinity DataIC50: 3.61E+4nMAssay Description:Inhibition of recombinant HNE (unknown origin) using N-methylsuccinyl-Ala-Ala-Pro-Val-7-amino-4-methylcoumarin, as a substrate measured every 30 sec ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/18/2021
Entry Details Article
PubMed
TargetM-phase inducer phosphatase 1(Human)
Montana State University

Curated by ChEMBL
LigandPNGBDBM50504347(CHEMBL365781)
Affinity DataIC50: 5.40E+3nMAssay Description:Inhibition of CDC25A (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/21/2024
Entry Details
PubMed
TargetM-phase inducer phosphatase 2(Human)
Montana State University

Curated by ChEMBL
LigandPNGBDBM50504347(CHEMBL365781)
Affinity DataIC50: 5.20E+3nMAssay Description:Inhibition of CDC25B (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/21/2024
Entry Details
PubMed