BDBM50504257 CHEMBL4535881

SMILES O=C(Nc1nnc(o1)-c1cccnc1)Nc1ccccc1

InChI Key InChIKey=WUSUAGWTYDFIBL-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50504257   

TargetProstaglandin G/H synthase 1(Sheep)
Cairo University

Curated by ChEMBL
LigandPNGBDBM50504257(CHEMBL4535881)
Affinity DataIC50: 9.37E+3nMAssay Description:Inhibition of ovine COX-1 by EIA methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/18/2021
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 2(Human)
Cairo University

Curated by ChEMBL
LigandPNGBDBM50504257(CHEMBL4535881)
Affinity DataIC50: 170nMAssay Description:Inhibition of human recombinant COX-2 by EIA methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/18/2021
Entry Details Article
PubMed
TargetEpidermal growth factor receptor(Human)
Cairo University

Curated by ChEMBL
LigandPNGBDBM50504257(CHEMBL4535881)
Affinity DataIC50: 276nMAssay Description:Inhibition of recombinant human GST-tagged EGFR catalytic domain (668 to 1210 residues) expressed in baculovirus expression system using TK-biotin pe...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/18/2021
Entry Details Article
PubMed