BDBM50504228 CHEMBL4437281

SMILES NS(=O)(=O)c1ccc(cc1)-n1nnc(-c2nnc(SCC(=O)c3ccc(Br)cc3)[nH]2)c1-c1ccccc1

InChI Key InChIKey=IFMKIYAEAJYEFB-UHFFFAOYSA-N

Data  4 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50504228   

TargetCarbonic anhydrase 4(Human)
Kurukshetra University

Curated by ChEMBL
LigandPNGBDBM50504228(CHEMBL4437281)
Affinity DataKi:  38nMAssay Description:Inhibition of human carbonic anhydrase 4 assessed as reduction in CO2 hydration incubated for 1 hr by phenol red staining-based stopped flow assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/18/2021
Entry Details Article
PubMed
TargetCarbonic anhydrase 2(Human)
Kurukshetra University

Curated by ChEMBL
LigandPNGBDBM50504228(CHEMBL4437281)
Affinity DataKi:  85nMAssay Description:Inhibition of human carbonic anhydrase 2 assessed as reduction in CO2 hydration incubated for 1 hr by phenol red staining-based stopped flow assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/18/2021
Entry Details Article
PubMed
TargetCarbonic anhydrase 9(Human)
Kurukshetra University

Curated by ChEMBL
LigandPNGBDBM50504228(CHEMBL4437281)
Affinity DataKi:  177nMAssay Description:Inhibition of human carbonic anhydrase 9 assessed as reduction in CO2 hydration incubated for 1 hr by phenol red staining-based stopped flow assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/18/2021
Entry Details Article
PubMed
TargetCarbonic anhydrase 1(Human)
Kurukshetra University

Curated by ChEMBL
LigandPNGBDBM50504228(CHEMBL4437281)
Affinity DataKi:  379nMAssay Description:Inhibition of human carbonic anhydrase 1 assessed as reduction in CO2 hydration incubated for 1 hr by phenol red staining-based stopped flow assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/18/2021
Entry Details Article
PubMed