BDBM50504153 CHEMBL4568748

SMILES CC1(NC(=O)N(CC(=O)Nc2ccc(c(c2)S(=O)(=O)N2CCCCC2)C(F)(F)F)C1=O)C1CC1

InChI Key InChIKey=YEFMHVVTDOGSGL-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50504153   

TargetBromodomain-containing protein 4(Human)
Cellzome

Curated by ChEMBL
LigandPNGBDBM50504153(CHEMBL4568748)
Affinity DataIC50: 5.01E+4nMAssay Description:Displacement of Alexa Fluor 647 labelled ligand from His6-tagged BRD4 BD1 (1 to 477 residues)/BD2 Y390A mutant (unknown origin) after 30 mins by TR-F...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/18/2021
Entry Details Article
PubMed
TargetBromodomain-containing protein 4(Human)
Cellzome

Curated by ChEMBL
LigandPNGBDBM50504153(CHEMBL4568748)
Affinity DataIC50: 2.51E+4nMAssay Description:Displacement of Alexa Fluor 647 labelled ligand from His6-tagged BRD4 BD2 (1 to 477 residues)/BD1 Y97A mutant (unknown origin) after 30 mins by TR-FR...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/18/2021
Entry Details Article
PubMed
LigandPNGBDBM50504153(CHEMBL4568748)
Affinity DataIC50: 1.00E+4nMAssay Description:Displacement of SGRG-K(Ac)-GG-K(Ac)-GLG-K(Ac)-GGAKRHRKV-biotin) from His6/FLAG-tagged TEV fused ATAD2 bromodomain (981 to 1121 residues) (unknown ori...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/18/2021
Entry Details Article
PubMed