BDBM50504109 CHEMBL4447110

SMILES Cc1c(oc2ccc(C)cc12)-c1n(nc2c1c(N)n[nH]c2=O)-c1ccc(NC(=O)\C=C\CN2CCOCC2)cc1

InChI Key InChIKey=UPGIHICOGVAEBN-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50504109   

TargetFibroblast growth factor receptor 2(Human)
Shanghai University

Curated by ChEMBL
LigandPNGBDBM50504109(CHEMBL4447110)
Affinity DataIC50: 8nMAssay Description:Inhibition of human FGFR2 using poly (Glu, Tyr)4:1 as substrate measured after 60 mins by ELISAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/18/2021
Entry Details Article
PubMed
TargetFibroblast growth factor receptor 1(Human)
Shanghai University

Curated by ChEMBL
LigandPNGBDBM50504109(CHEMBL4447110)
Affinity DataIC50: 31nMAssay Description:Inhibition of human FGFR1 using poly (Glu, Tyr)4:1 as substrate measured after 60 mins by ELISAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/18/2021
Entry Details Article
PubMed