BDBM50504106 CHEMBL4462946

SMILES CN(C)C\C=C\C(=O)Nc1ccc(cc1)-n1nc2c(c1-c1oc3ccc(Cl)cc3c1C)c(N)n[nH]c2=O

InChI Key InChIKey=IJOGTDNCYKJLOQ-UHFFFAOYSA-N

Data  1 KI  5 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 50504106   

TargetFibroblast growth factor receptor 1(Human)
Shanghai University

Curated by ChEMBL
LigandPNGBDBM50504106(CHEMBL4462946)
Affinity DataIC50: 20nMAssay Description:Inhibition of human FGFR1 using poly (Glu, Tyr)4:1 as substrate measured after 60 mins by ELISAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/18/2021
Entry Details Article
PubMed
TargetFibroblast growth factor receptor 2(Human)
Shanghai University

Curated by ChEMBL
LigandPNGBDBM50504106(CHEMBL4462946)
Affinity DataIC50: 7.20nMAssay Description:Inhibition of human FGFR2 using poly (Glu, Tyr)4:1 as substrate measured after 60 mins by ELISAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/18/2021
Entry Details Article
PubMed
TargetPotassium voltage-gated channel subfamily H member 2(Human)
Shanghai University

Curated by ChEMBL
LigandPNGBDBM50504106(CHEMBL4462946)
Affinity DataIC50: 4.00E+4nMAssay Description:Inhibition of human ERG by patch-clamp methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/18/2021
Entry Details Article
PubMed
TargetFibroblast growth factor receptor 1(Human)
Shanghai University

Curated by ChEMBL
LigandPNGBDBM50504106(CHEMBL4462946)
Affinity DataIC50: 20nMAssay Description:Inhibition of FGFR1 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/18/2024
Entry Details
PubMed
TargetFibroblast growth factor receptor 2(Human)
Shanghai University

Curated by ChEMBL
LigandPNGBDBM50504106(CHEMBL4462946)
Affinity DataIC50: 7.20nMAssay Description:Inhibition of FGFR2 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/18/2024
Entry Details
PubMed
TargetFibroblast growth factor receptor 1(Human)
Shanghai University

Curated by ChEMBL
LigandPNGBDBM50504106(CHEMBL4462946)
Affinity DataKi:  10nMAssay Description:Irreversible inhibition of human FGFR1 using poly (Glu, Tyr)4:1 as substrate measured after 60 minsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/18/2021
Entry Details Article
PubMed