BDBM50504103 CHEMBL4463714

SMILES CN(C)C\C=C\C(=O)Nc1ccc(cc1)-n1nc2c(c1-c1oc3ccc(C)cc3c1C)c(N)n[nH]c2=O

InChI Key InChIKey=GITNDHUJOBXSCE-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50504103   

TargetFibroblast growth factor receptor 2(Human)
Shanghai University

Curated by ChEMBL
LigandPNGBDBM50504103(CHEMBL4463714)
Affinity DataIC50: 1.90nMAssay Description:Inhibition of human FGFR2 using poly (Glu, Tyr)4:1 as substrate measured after 60 mins by ELISAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/18/2021
Entry Details Article
PubMed
TargetFibroblast growth factor receptor 1(Human)
Shanghai University

Curated by ChEMBL
LigandPNGBDBM50504103(CHEMBL4463714)
Affinity DataIC50: 2.40nMAssay Description:Inhibition of human FGFR1 using poly (Glu, Tyr)4:1 as substrate measured after 60 mins by ELISAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/18/2021
Entry Details Article
PubMed
TargetPotassium voltage-gated channel subfamily H member 2(Human)
Shanghai University

Curated by ChEMBL
LigandPNGBDBM50504103(CHEMBL4463714)
Affinity DataIC50: 3.29E+4nMAssay Description:Inhibition of human ERG by patch-clamp methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/18/2021
Entry Details Article
PubMed
TargetFibroblast growth factor receptor 1(Human)
Shanghai University

Curated by ChEMBL
LigandPNGBDBM50504103(CHEMBL4463714)
Affinity DataIC50: 3nMAssay Description:Inhibition of human FGFR1More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/21/2024
Entry Details
PubMed