BDBM50504051 CHEMBL4450502

SMILES CC1=CC[C@]2(C[C@@H]1O)[C@@H](CC[C@@H]2C(O)=O)C1CCCCC1

InChI Key InChIKey=ZEQATYGPOXRDTP-UHFFFAOYSA-N

Data  1 KI  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50504051   

Target11-beta-hydroxysteroid dehydrogenase 1(Human)
The University of Tennessee Health Science Center

Curated by ChEMBL
LigandPNGBDBM50504051(CHEMBL4450502)
Affinity DataIC50: 1.34E+3nMAssay Description:Inhibition of N-terminal MKHQHQHQHQHQHQQPL-tagged 11beta-HSD1 C272S mutant (unknown origin) expressed in Escherichia coli BL21 (DE3) using cortisol a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/18/2021
Entry Details Article
PubMed
Target11-beta-hydroxysteroid dehydrogenase type 2(Human)
The University of Tennessee Health Science Center

Curated by ChEMBL
LigandPNGBDBM50504051(CHEMBL4450502)
Affinity DataIC50: 5.00E+5nMAssay Description:Inhibition of 11beta-HSD2 (unknown origin) expressed in HEK293 cells using cortisone as substrate measured after 2 hrs in presence of NAD+ by HTRF as...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/18/2021
Entry Details Article
PubMed
Target11-beta-hydroxysteroid dehydrogenase 1(Human)
The University of Tennessee Health Science Center

Curated by ChEMBL
LigandPNGBDBM50504051(CHEMBL4450502)
Affinity DataKi:  210nMAssay Description:Inhibition of N-terminal MKHQHQHQHQHQHQQPL-tagged 11beta-HSD1 C272S mutant (unknown origin) expressed in Escherichia coli BL21 (DE3) using cortisol a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/18/2021
Entry Details Article
PubMed