BDBM50504034 CHEMBL4588384

SMILES Nc1n[nH]c(n1)N1CCC(CC1)N1CCC[C@@H]1Cc1ccc(Cl)cc1

InChI Key InChIKey=RNAWZJCKLNMMPX-UHFFFAOYSA-N

Data  5 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50504034   

TargetChitotriosidase-1(Human)
Oncoarendi Therapeutics

Curated by ChEMBL
LigandPNGBDBM50504034(CHEMBL4588384)
Affinity DataIC50: 59nMAssay Description:Inhibition of full-length C-terminal his-tagged human CHIT1 expressed in CHOK1 cells assessed as reduction in chitinolytic activity using 4-methylumb...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/18/2021
Entry Details Article
PubMed
TargetAcidic mammalian chitinase(Human)
Oncoarendi Therapeutics

Curated by ChEMBL
LigandPNGBDBM50504034(CHEMBL4588384)
Affinity DataIC50: 73nMAssay Description:Inhibition of full-length C-terminal his-tagged human acidic mammalian chitinase expressed in CHOK1 cells assessed as reduction in chitinolytic activ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/18/2021
Entry Details Article
PubMed
TargetChitotriosidase-1(Mouse)
Oncoarendi Therapeutics

Curated by ChEMBL
LigandPNGBDBM50504034(CHEMBL4588384)
Affinity DataIC50: 430nMAssay Description:Inhibition of full-length C-terminal his-tagged mouse CHIT1 expressed in CHO-K1 cells assessed as reduction in chitinolytic activity using 4-methylum...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/18/2021
Entry Details Article
PubMed
TargetPotassium voltage-gated channel subfamily H member 2(Human)
Oncoarendi Therapeutics

Curated by ChEMBL
LigandPNGBDBM50504034(CHEMBL4588384)
Affinity DataIC50: 4.00E+3nMAssay Description:Displacement of Tracer Red from human ERG by fluorescence polarization assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/18/2021
Entry Details Article
PubMed
TargetAcidic mammalian chitinase(Mouse)
Oncoarendi Therapeutics

Curated by ChEMBL
LigandPNGBDBM50504034(CHEMBL4588384)
Affinity DataIC50: 120nMAssay Description:Inhibition of full-length C-terminal his-tagged mouse acidic mammalian chitinase expressed in CHO-K1 cells assessed as reduction in chitinolytic acti...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/18/2021
Entry Details Article
PubMed