BDBM50504025 CHEMBL4464754

SMILES Nc1n[nH]c(n1)N1CCC(CC1)N(CCc1ccc(Cl)cc1)CC1CCCCO1

InChI Key InChIKey=SRBNCTZWNGFYDI-UHFFFAOYSA-N

Data  5 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50504025   

TargetPotassium voltage-gated channel subfamily H member 2(Human)
Oncoarendi Therapeutics

Curated by ChEMBL
LigandPNGBDBM50504025(CHEMBL4464754)
Affinity DataIC50: 1.10E+4nMAssay Description:Displacement of Tracer Red from human ERG by fluorescence polarization assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/18/2021
Entry Details Article
PubMed
TargetAcidic mammalian chitinase(Mouse)
Oncoarendi Therapeutics

Curated by ChEMBL
LigandPNGBDBM50504025(CHEMBL4464754)
Affinity DataIC50: 56nMAssay Description:Inhibition of full-length C-terminal his-tagged mouse acidic mammalian chitinase expressed in CHO-K1 cells assessed as reduction in chitinolytic acti...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/18/2021
Entry Details Article
PubMed
TargetChitotriosidase-1(Mouse)
Oncoarendi Therapeutics

Curated by ChEMBL
LigandPNGBDBM50504025(CHEMBL4464754)
Affinity DataIC50: 750nMAssay Description:Inhibition of full-length C-terminal his-tagged mouse CHIT1 expressed in CHO-K1 cells assessed as reduction in chitinolytic activity using 4-methylum...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/18/2021
Entry Details Article
PubMed
TargetChitotriosidase-1(Human)
Oncoarendi Therapeutics

Curated by ChEMBL
LigandPNGBDBM50504025(CHEMBL4464754)
Affinity DataIC50: 21nMAssay Description:Inhibition of full-length C-terminal his-tagged human CHIT1 expressed in CHOK1 cells assessed as reduction in chitinolytic activity using 4-methylumb...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/18/2021
Entry Details Article
PubMed
TargetAcidic mammalian chitinase(Human)
Oncoarendi Therapeutics

Curated by ChEMBL
LigandPNGBDBM50504025(CHEMBL4464754)
Affinity DataIC50: 68nMAssay Description:Inhibition of full-length C-terminal his-tagged human acidic mammalian chitinase expressed in CHOK1 cells assessed as reduction in chitinolytic activ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/18/2021
Entry Details Article
PubMed