BDBM50504015 CHEMBL4555101

SMILES CNC(=O)NCCN(CCc1ccc(Cl)cc1)C1CCN(CC1)c1nc(N)n[nH]1

InChI Key InChIKey=ARWWVAZVGCKBKL-UHFFFAOYSA-N

Data  5 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50504015   

TargetChitotriosidase-1(Mouse)
Oncoarendi Therapeutics

Curated by ChEMBL
LigandPNGBDBM50504015(CHEMBL4555101)
Affinity DataIC50: 9.10E+3nMAssay Description:Inhibition of full-length C-terminal his-tagged mouse CHIT1 expressed in CHO-K1 cells assessed as reduction in chitinolytic activity using 4-methylum...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/18/2021
Entry Details Article
PubMed
TargetPotassium voltage-gated channel subfamily H member 2(Human)
Oncoarendi Therapeutics

Curated by ChEMBL
LigandPNGBDBM50504015(CHEMBL4555101)
Affinity DataIC50: 1.80E+3nMAssay Description:Displacement of Tracer Red from human ERG by fluorescence polarization assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/18/2021
Entry Details Article
PubMed
TargetChitotriosidase-1(Human)
Oncoarendi Therapeutics

Curated by ChEMBL
LigandPNGBDBM50504015(CHEMBL4555101)
Affinity DataIC50: 1.43E+3nMAssay Description:Inhibition of full-length C-terminal his-tagged human CHIT1 expressed in CHOK1 cells assessed as reduction in chitinolytic activity using 4-methylumb...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/18/2021
Entry Details Article
PubMed
TargetAcidic mammalian chitinase(Human)
Oncoarendi Therapeutics

Curated by ChEMBL
LigandPNGBDBM50504015(CHEMBL4555101)
Affinity DataIC50: 425nMAssay Description:Inhibition of full-length C-terminal his-tagged human acidic mammalian chitinase expressed in CHOK1 cells assessed as reduction in chitinolytic activ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/18/2021
Entry Details Article
PubMed
TargetAcidic mammalian chitinase(Mouse)
Oncoarendi Therapeutics

Curated by ChEMBL
LigandPNGBDBM50504015(CHEMBL4555101)
Affinity DataIC50: 130nMAssay Description:Inhibition of full-length C-terminal his-tagged mouse acidic mammalian chitinase expressed in CHO-K1 cells assessed as reduction in chitinolytic acti...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/18/2021
Entry Details Article
PubMed