BDBM50503783 CHEMBL4590754

SMILES Cc1cc(cc(C)c1S(N)(=O)=O)N1CC(CC1=O)C(=O)NN1CC(CC1=O)C(O)=O

InChI Key InChIKey=TZMUZODFGLCMBN-UHFFFAOYSA-N

Data  18 Kd

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 18 hits for monomerid = 50503783   

TargetCarbonic anhydrase 13(Human)
Kaunas University of Technology

Curated by ChEMBL
LigandPNGBDBM50503783(CHEMBL4590754)
Affinity DataKd:  6.70E+3nMAssay Description:Binding affinity to recombinant human CA13 by DSF-based fluorescence thermal shift assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/18/2021
Entry Details Article
PubMed
TargetCarbonic anhydrase 12(Human)
Kaunas University of Technology

Curated by ChEMBL
LigandPNGBDBM50503783(CHEMBL4590754)
Affinity DataKd:  1.40nMAssay Description:Binding affinity to recombinant human CA12 assessed as intrinsic dissociation constant by DSF-based fluorescence thermal shift assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/18/2021
Entry Details Article
PubMed
TargetCarbonic anhydrase 9(Human)
Kaunas University of Technology

Curated by ChEMBL
LigandPNGBDBM50503783(CHEMBL4590754)
Affinity DataKd:  0.190nMAssay Description:Binding affinity to recombinant human CA9 assessed as intrinsic dissociation constant by DSF-based fluorescence thermal shift assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/18/2021
Entry Details Article
PubMed
TargetCarbonic anhydrase 13(Human)
Kaunas University of Technology

Curated by ChEMBL
LigandPNGBDBM50503783(CHEMBL4590754)
Affinity DataKd:  0.990nMAssay Description:Binding affinity to recombinant human CA13 assessed as intrinsic dissociation constant by DSF-based fluorescence thermal shift assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/18/2021
Entry Details Article
PubMed
TargetCarbonic anhydrase 2(Human)
Kaunas University of Technology

Curated by ChEMBL
LigandPNGBDBM50503783(CHEMBL4590754)
Affinity DataKd:  7.10E+3nMAssay Description:Binding affinity to recombinant human CA2 by DSF-based fluorescence thermal shift assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/18/2021
Entry Details Article
PubMed
TargetCarbonic anhydrase 6(Human)
Kaunas University of Technology

Curated by ChEMBL
LigandPNGBDBM50503783(CHEMBL4590754)
Affinity DataKd:  8.30E+4nMAssay Description:Binding affinity to recombinant human CA6 by DSF-based fluorescence thermal shift assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/18/2021
Entry Details Article
PubMed
TargetCarbonic anhydrase 5B, mitochondrial(Human)
Kaunas University of Technology

Curated by ChEMBL
LigandPNGBDBM50503783(CHEMBL4590754)
Affinity DataKd:  7.70E+3nMAssay Description:Binding affinity to recombinant full length N-terminal His6x-tagged human CA5B expressed in Escherichia coli Rosetta 2 (DE3) by DSF-based fluorescenc...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/18/2021
Entry Details Article
PubMed
TargetCarbonic anhydrase 7(Human)
Kaunas University of Technology

Curated by ChEMBL
LigandPNGBDBM50503783(CHEMBL4590754)
Affinity DataKd:  3.30E+4nMAssay Description:Binding affinity to recombinant human CA7 by DSF-based fluorescence thermal shift assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/18/2021
Entry Details Article
PubMed
TargetCarbonic anhydrase 4(Human)
Kaunas University of Technology

Curated by ChEMBL
LigandPNGBDBM50503783(CHEMBL4590754)
Affinity DataKd:  9.10E+3nMAssay Description:Binding affinity to recombinant human CA4 by DSF-based fluorescence thermal shift assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/18/2021
Entry Details Article
PubMed
TargetCarbonic anhydrase 1(Human)
Kaunas University of Technology

Curated by ChEMBL
LigandPNGBDBM50503783(CHEMBL4590754)
Affinity DataKd:  1.90nMAssay Description:Binding affinity to recombinant human CA1 assessed as intrinsic dissociation constant by DSF-based fluorescence thermal shift assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/18/2021
Entry Details Article
PubMed
TargetCarbonic anhydrase 12(Human)
Kaunas University of Technology

Curated by ChEMBL
LigandPNGBDBM50503783(CHEMBL4590754)
Affinity DataKd:  2.20E+4nMAssay Description:Binding affinity to recombinant human CA12 by DSF-based fluorescence thermal shift assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/18/2021
Entry Details Article
PubMed
TargetCarbonic anhydrase 9(Human)
Kaunas University of Technology

Curated by ChEMBL
LigandPNGBDBM50503783(CHEMBL4590754)
Affinity DataKd:  4.00E+3nMAssay Description:Binding affinity to recombinant human CA9 by DSF-based fluorescence thermal shift assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/18/2021
Entry Details Article
PubMed
TargetCarbonic anhydrase 4(Human)
Kaunas University of Technology

Curated by ChEMBL
LigandPNGBDBM50503783(CHEMBL4590754)
Affinity DataKd:  0.420nMAssay Description:Binding affinity to recombinant human CA4 assessed as intrinsic dissociation constant by DSF-based fluorescence thermal shift assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/18/2021
Entry Details Article
PubMed
TargetCarbonic anhydrase 2(Human)
Kaunas University of Technology

Curated by ChEMBL
LigandPNGBDBM50503783(CHEMBL4590754)
Affinity DataKd:  0.520nMAssay Description:Binding affinity to recombinant human CA2 assessed as intrinsic dissociation constant by DSF-based fluorescence thermal shift assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/18/2021
Entry Details Article
PubMed
TargetCarbonic anhydrase 7(Human)
Kaunas University of Technology

Curated by ChEMBL
LigandPNGBDBM50503783(CHEMBL4590754)
Affinity DataKd:  2.10nMAssay Description:Binding affinity to recombinant human CA7 assessed as intrinsic dissociation constant by DSF-based fluorescence thermal shift assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/18/2021
Entry Details Article
PubMed
TargetCarbonic anhydrase 1(Human)
Kaunas University of Technology

Curated by ChEMBL
LigandPNGBDBM50503783(CHEMBL4590754)
Affinity DataKd:  1.30E+4nMAssay Description:Binding affinity to recombinant human CA1 by DSF-based fluorescence thermal shift assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/18/2021
Entry Details Article
PubMed
TargetCarbonic anhydrase 6(Human)
Kaunas University of Technology

Curated by ChEMBL
LigandPNGBDBM50503783(CHEMBL4590754)
Affinity DataKd:  1.20nMAssay Description:Binding affinity to recombinant human CA6 assessed as intrinsic dissociation constant by DSF-based fluorescence thermal shift assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/18/2021
Entry Details Article
PubMed
TargetCarbonic anhydrase 5B, mitochondrial(Human)
Kaunas University of Technology

Curated by ChEMBL
LigandPNGBDBM50503783(CHEMBL4590754)
Affinity DataKd:  0.630nMAssay Description:Binding affinity to recombinant full length N-terminal His6x-tagged human CA5B expressed in Escherichia coli Rosetta 2 (DE3) assessed as intrinsic di...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/18/2021
Entry Details Article
PubMed