BDBM50503782 CHEMBL4454574

SMILES Cc1cc(c(C)cc1N1CC(CC1=O)C(=O)NN)S(N)(=O)=O

InChI Key InChIKey=QKRANWMIHBZHSL-UHFFFAOYSA-N

Data  20 Kd

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 20 hits for monomerid = 50503782   

TargetCarbonic anhydrase 9(Human)
Kaunas University of Technology

Curated by ChEMBL
LigandPNGBDBM50503782(CHEMBL4454574)
Affinity DataKd:  9.00E+3nMAssay Description:Binding affinity to recombinant human CA9 by DSF-based fluorescence thermal shift assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/18/2021
Entry Details Article
PubMed
TargetCarbonic anhydrase 2(Human)
Kaunas University of Technology

Curated by ChEMBL
LigandPNGBDBM50503782(CHEMBL4454574)
Affinity DataKd:  2.70nMAssay Description:Binding affinity to recombinant human CA2 assessed as intrinsic dissociation constant by DSF-based fluorescence thermal shift assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/18/2021
Entry Details Article
PubMed
TargetCarbonic anhydrase 1(Human)
Kaunas University of Technology

Curated by ChEMBL
LigandPNGBDBM50503782(CHEMBL4454574)
Affinity DataKd:  5.80E+4nMAssay Description:Binding affinity to recombinant human CA1 by DSF-based fluorescence thermal shift assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/18/2021
Entry Details Article
PubMed
TargetCarbonic anhydrase 5B, mitochondrial(Human)
Kaunas University of Technology

Curated by ChEMBL
LigandPNGBDBM50503782(CHEMBL4454574)
Affinity DataKd:  660nMAssay Description:Binding affinity to recombinant full length N-terminal His6x-tagged human CA5B expressed in Escherichia coli Rosetta 2 (DE3) by DSF-based fluorescenc...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/18/2021
Entry Details Article
PubMed
TargetCarbonic anhydrase 2(Human)
Kaunas University of Technology

Curated by ChEMBL
LigandPNGBDBM50503782(CHEMBL4454574)
Affinity DataKd:  8.10E+3nMAssay Description:Binding affinity to recombinant human CA2 by DSF-based fluorescence thermal shift assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/18/2021
Entry Details Article
PubMed
TargetCarbonic anhydrase 1(Human)
Kaunas University of Technology

Curated by ChEMBL
LigandPNGBDBM50503782(CHEMBL4454574)
Affinity DataKd:  41nMAssay Description:Binding affinity to recombinant human CA1 assessed as intrinsic dissociation constant by DSF-based fluorescence thermal shift assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/18/2021
Entry Details Article
PubMed
TargetCarbonic anhydrase 7(Human)
Kaunas University of Technology

Curated by ChEMBL
LigandPNGBDBM50503782(CHEMBL4454574)
Affinity DataKd:  4.40E+3nMAssay Description:Binding affinity to recombinant human CA7 by DSF-based fluorescence thermal shift assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/18/2021
Entry Details Article
PubMed
TargetCarbonic anhydrase 6(Human)
Kaunas University of Technology

Curated by ChEMBL
LigandPNGBDBM50503782(CHEMBL4454574)
Affinity DataKd:  2.40E+4nMAssay Description:Binding affinity to recombinant human CA6 by DSF-based fluorescence thermal shift assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/18/2021
Entry Details Article
PubMed
TargetCarbonic anhydrase 4(Human)
Kaunas University of Technology

Curated by ChEMBL
LigandPNGBDBM50503782(CHEMBL4454574)
Affinity DataKd:  1.40E+4nMAssay Description:Binding affinity to recombinant human CA4 by DSF-based fluorescence thermal shift assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/18/2021
Entry Details Article
PubMed
TargetCarbonic anhydrase 13(Human)
Kaunas University of Technology

Curated by ChEMBL
LigandPNGBDBM50503782(CHEMBL4454574)
Affinity DataKd:  2.80E+3nMAssay Description:Binding affinity to recombinant human CA13 by DSF-based fluorescence thermal shift assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/18/2021
Entry Details Article
PubMed
TargetCarbonic anhydrase 14(Human)
Kaunas University of Technology

Curated by ChEMBL
LigandPNGBDBM50503782(CHEMBL4454574)
Affinity DataKd:  4.00E+3nMAssay Description:Binding affinity to recombinant N-terminal His6x-tagged human CA14 (20 to 280 residues) catalytic domain expressed in Escherichia coli Rosetta 2 (DE3...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/18/2021
Entry Details Article
PubMed
TargetCarbonic anhydrase 5B, mitochondrial(Human)
Kaunas University of Technology

Curated by ChEMBL
LigandPNGBDBM50503782(CHEMBL4454574)
Affinity DataKd:  0.25nMAssay Description:Binding affinity to recombinant full length N-terminal His6x-tagged human CA5B expressed in Escherichia coli Rosetta 2 (DE3) assessed as intrinsic di...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/18/2021
Entry Details Article
PubMed
TargetCarbonic anhydrase 4(Human)
Kaunas University of Technology

Curated by ChEMBL
LigandPNGBDBM50503782(CHEMBL4454574)
Affinity DataKd:  3nMAssay Description:Binding affinity to recombinant human CA4 assessed as intrinsic dissociation constant by DSF-based fluorescence thermal shift assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/18/2021
Entry Details Article
PubMed
TargetCarbonic anhydrase 13(Human)
Kaunas University of Technology

Curated by ChEMBL
LigandPNGBDBM50503782(CHEMBL4454574)
Affinity DataKd:  1.90nMAssay Description:Binding affinity to recombinant human CA13 assessed as intrinsic dissociation constant by DSF-based fluorescence thermal shift assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/18/2021
Entry Details Article
PubMed
TargetCarbonic anhydrase 12(Human)
Kaunas University of Technology

Curated by ChEMBL
LigandPNGBDBM50503782(CHEMBL4454574)
Affinity DataKd:  6.20nMAssay Description:Binding affinity to recombinant human CA12 assessed as intrinsic dissociation constant by DSF-based fluorescence thermal shift assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/18/2021
Entry Details Article
PubMed
TargetCarbonic anhydrase 9(Human)
Kaunas University of Technology

Curated by ChEMBL
LigandPNGBDBM50503782(CHEMBL4454574)
Affinity DataKd:  1.90nMAssay Description:Binding affinity to recombinant human CA9 assessed as intrinsic dissociation constant by DSF-based fluorescence thermal shift assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/18/2021
Entry Details Article
PubMed
TargetCarbonic anhydrase 7(Human)
Kaunas University of Technology

Curated by ChEMBL
LigandPNGBDBM50503782(CHEMBL4454574)
Affinity DataKd:  1.30nMAssay Description:Binding affinity to recombinant human CA7 assessed as intrinsic dissociation constant by DSF-based fluorescence thermal shift assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/18/2021
Entry Details Article
PubMed
TargetCarbonic anhydrase 12(Human)
Kaunas University of Technology

Curated by ChEMBL
LigandPNGBDBM50503782(CHEMBL4454574)
Affinity DataKd:  2.10E+4nMAssay Description:Binding affinity to recombinant human CA12 by DSF-based fluorescence thermal shift assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/18/2021
Entry Details Article
PubMed
TargetCarbonic anhydrase 6(Human)
Kaunas University of Technology

Curated by ChEMBL
LigandPNGBDBM50503782(CHEMBL4454574)
Affinity DataKd:  1.70nMAssay Description:Binding affinity to recombinant human CA6 assessed as intrinsic dissociation constant by DSF-based fluorescence thermal shift assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/18/2021
Entry Details Article
PubMed
TargetCarbonic anhydrase 14(Human)
Kaunas University of Technology

Curated by ChEMBL
LigandPNGBDBM50503782(CHEMBL4454574)
Affinity DataKd:  0.340nMAssay Description:Binding affinity to recombinant N-terminal His6x-tagged human CA14 (20 to 280 residues) catalytic domain expressed in Escherichia coli Rosetta 2 (DE3...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/18/2021
Entry Details Article
PubMed