BDBM50503750 CHEMBL4516770

SMILES CC1(C)CC(CC(C)(C)N1O)NC(=O)c1ccc(Nc2ncc(c(Nc3ccc(cc3)C(=O)Nc3ccc(Cl)cc3)n2)[N+]([O-])=O)cc1

InChI Key InChIKey=DZNYEACQQUFYOH-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50503750   

TargetAurora kinase A(Human)
Lanzhou University

Curated by ChEMBL
LigandPNGBDBM50503750(CHEMBL4516770)
Affinity DataIC50: 20nMAssay Description:Inhibition of Aurora A (unknown origin) using kemptide acetate salt as substrate after 30 mins by kinase-Glo luminescence methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/18/2021
Entry Details Article
PubMed
TargetAurora kinase B(Human)
Lanzhou University

Curated by ChEMBL
LigandPNGBDBM50503750(CHEMBL4516770)
Affinity DataIC50: 0.670nMAssay Description:Inhibition of Aurora B (unknown origin) using kemptide acetate salt as substrate after 30 mins by kinase-Glo luminescence methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/18/2021
Entry Details Article
PubMed