BDBM50503476 CHEMBL4578758

SMILES Cc1ncccc1OCc1cc2nc(cc(-c3ccc(F)cc3)c2s1)C(N)=O

InChI Key InChIKey=XFGLQGCIKTVKOK-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50503476   

TargetMetabotropic glutamate receptor 2(Rat)
Vanderbilt University School of Medicine

Curated by ChEMBL
LigandPNGBDBM50503476(CHEMBL4578758)
Affinity DataIC50: 759nMAssay Description:Negative allosteric modulation of rat mGlu2R expressed in HEK293 cells co-expressing Galpha15 assessed as decrease in glutamate-induced calcium mobil...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/18/2021
Entry Details Article
PubMed
TargetMetabotropic glutamate receptor 2(Rat)
Vanderbilt University School of Medicine

Curated by ChEMBL
LigandPNGBDBM50503476(CHEMBL4578758)
Affinity DataIC50: 759nMAssay Description:Negative allosteric modulation of rat mGlu2R expressed in HEK293 cells co-expressing Galpha15 assessed as decrease in glutamate-induced calcium mobil...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/18/2021
Entry Details Article
PubMed