BDBM50503459 CHEMBL4475753

SMILES COc1ccc(cc1)-c1cc(nc2cc(COc3cnc(C)nc3)sc12)C(N)=O

InChI Key InChIKey=ZPTCDLHDLQDUPO-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50503459   

TargetMetabotropic glutamate receptor 2(Rat)
Vanderbilt University School of Medicine

Curated by ChEMBL
LigandPNGBDBM50503459(CHEMBL4475753)
Affinity DataIC50: 316nMAssay Description:Negative allosteric modulation of rat mGlu2R expressed in HEK293 cells co-expressing Galpha15 assessed as decrease in glutamate-induced calcium mobil...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/18/2021
Entry Details Article
PubMed
TargetMetabotropic glutamate receptor 2(Rat)
Vanderbilt University School of Medicine

Curated by ChEMBL
LigandPNGBDBM50503459(CHEMBL4475753)
Affinity DataIC50: 316nMAssay Description:Negative allosteric modulation of rat mGlu2R expressed in HEK293 cells co-expressing Galpha15 assessed as decrease in glutamate-induced calcium mobil...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/18/2021
Entry Details Article
PubMed
TargetMetabotropic glutamate receptor 2(Rat)
Vanderbilt University School of Medicine

Curated by ChEMBL
LigandPNGBDBM50503459(CHEMBL4475753)
Affinity DataIC50: 447nMAssay Description:Negative allosteric modulation of rat mGlu2R expressed in HEK293 cells co-expressing Galpha15 assessed as decrease in glutamate-induced calcium mobil...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/18/2021
Entry Details Article
PubMed
TargetMetabotropic glutamate receptor 2(Rat)
Vanderbilt University School of Medicine

Curated by ChEMBL
LigandPNGBDBM50503459(CHEMBL4475753)
Affinity DataIC50: 447nMAssay Description:Negative allosteric modulation of rat mGlu2R expressed in HEK293 cells co-expressing Galpha15 assessed as decrease in glutamate-induced calcium mobil...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/18/2021
Entry Details Article
PubMed