BDBM50503307 CHEMBL4466771

SMILES c1ccc(cc1)CC(=O)Nc2nnc(s2)[C@H]3CCC[C@@H](C3)c4nnc(s4)NC(=O)Cc5ccccc5

InChI Key InChIKey=CZRVPWLXPUBTMI-UHFFFAOYSA-N

Data  3 IC50

PDB links: 1 PDB ID matches this monomer.

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50503307   

LigandPNGBDBM50503307(CHEMBL4466771)
Affinity DataIC50: 100nMAssay Description:Inhibition of GAC (unknown origin) assessed as NADH formation using 1.8 to 13 mM glutamine as substrate preincubated for 60 mins by resorufin dye bas...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/18/2021
Entry Details Article
PubMedPDB3D3D Structure (crystal)
LigandPNGBDBM50503307(CHEMBL4466771)
Affinity DataIC50: 100nMAssay Description:Inhibition of GAC (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/19/2021
Entry Details Article
PubMedPDB3D3D Structure (crystal)
LigandPNGBDBM50503307(CHEMBL4466771)
Affinity DataIC50: 280nMAssay Description:Allosteric inhibition of human kidney glutaminase using [3H]-Glutamine as substrate in presence of inhibitor incubated for 45 mins by Perkin Elmer ba...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/22/2022
Entry Details Article
PubMedPDB3D3D Structure (crystal)