BDBM50503134 CHEMBL4447963

SMILES Cc1nc(NC(=O)CN)sc1-c1cnc(Cl)c(NS(=O)(=O)c2ccc(cc2)C(C)(C)C)c1

InChI Key InChIKey=YCVQOWKBUVDTOG-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50503134   

TargetPhosphatidylinositol 3-kinase catalytic subunit type 3(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50503134(CHEMBL4447963)
Affinity DataIC50: 19nMAssay Description:Inhibition of Vps34 (unknown origin) after 60 mins by ADP-Glo assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/18/2021
Entry Details Article
PubMed
LigandPNGBDBM50503134(CHEMBL4447963)
Affinity DataIC50: 6nMAssay Description:Inhibition of PI3K delta (unknown origin) after 60 mins by ADP-Glo assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/18/2021
Entry Details Article
PubMed
LigandPNGBDBM50503134(CHEMBL4447963)
Affinity DataIC50: 6nMAssay Description:Competitive inhibition of P13Kdelta (unknown origin) using PIP2:PS as substrate preincubated for 1 hr followed by substrate addition for 1 hr by ADP-...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/19/2024
Entry Details
PubMed
TargetPhosphatidylinositol 3-kinase catalytic subunit type 3(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50503134(CHEMBL4447963)
Affinity DataIC50: 19nMAssay Description:Competitive inhibition of Vps34 (unknown origin) using PI:PS as substrate preincubated for 1 hr followed by substrate addition for 1 hr by ADP-Glo as...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/19/2024
Entry Details
PubMed