BDBM50503094 CHEMBL4584933

SMILES COc1cc(ccc1Nc1cc2N(C3CCCC3)[C@H](C)C(=O)N(C)c2cc1F)C(=O)N1CCC(O)CC1

InChI Key InChIKey=APAQHFNUDRAUJT-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50503094   

TargetTranscription initiation factor TFIID subunit 1(Human)
Dana Farber Cancer Institute

Curated by ChEMBL
LigandPNGBDBM50503094(CHEMBL4584933)
Affinity DataIC50: 4.60E+3nMAssay Description:Displacement of biotinylated probe from human TAF1 bromodomain 2 (1522 to 1656 residues) expressed in Escherichia coli BL21 (DE3) by alphascreen assa...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/17/2021
Entry Details Article
PubMed
TargetBromodomain-containing protein 4(Human)
Dana Farber Cancer Institute

Curated by ChEMBL
LigandPNGBDBM50503094(CHEMBL4584933)
Affinity DataIC50: 680nMAssay Description:Displacement of Bio-JQ1 from recombinant human His6 tagged BRD4 bromodomain 1 by alphascreen assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/17/2021
Entry Details Article
PubMed