BDBM50503090 CHEMBL4466613

SMILES COc1cc(ccc1Nc1ccc2N(C)C(=O)[C@@H](C)N(C3CCCC3)c2n1)C(=O)N1CCC(O)CC1

InChI Key InChIKey=WDUULYPCWOELII-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50503090   

TargetTranscription initiation factor TFIID subunit 1(Human)
Dana Farber Cancer Institute

Curated by ChEMBL
LigandPNGBDBM50503090(CHEMBL4466613)
Affinity DataIC50: 93nMAssay Description:Displacement of biotinylated probe from human TAF1 bromodomain 2 (1522 to 1656 residues) expressed in Escherichia coli BL21 (DE3) by alphascreen assa...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/17/2021
Entry Details Article
PubMed
TargetBromodomain-containing protein 4(Human)
Dana Farber Cancer Institute

Curated by ChEMBL
LigandPNGBDBM50503090(CHEMBL4466613)
Affinity DataIC50: 47nMAssay Description:Displacement of Bio-JQ1 from recombinant human His6 tagged BRD4 bromodomain 1 by alphascreen assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/17/2021
Entry Details Article
PubMed