BDBM50502863 CHEMBL4542316

SMILES COc1cc2C(=NC(Cc2cc1OC1CCCC1)C(=O)Nc1cccc(c1)[N+]([O-])=O)c1ccccc1

InChI Key InChIKey=IMTDJROOIAERSI-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50502863   

TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4B(Human)
South China Agricultural University

Curated by ChEMBL
LigandPNGBDBM50502863(CHEMBL4542316)
Affinity DataIC50: 8.32E+3nMAssay Description:Inhibition of PDE4B in human U937 cells using [3H] cAMP as substrate incubated for 30 minsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/17/2021
Entry Details Article
PubMed
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4D(Human)
South China Agricultural University

Curated by ChEMBL
LigandPNGBDBM50502863(CHEMBL4542316)
Affinity DataIC50: 3.74E+4nMAssay Description:Inhibition of PDE4D in human U937 cells using [3H]cAMP as substrate incubated for 30 minsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/17/2021
Entry Details Article
PubMed
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4B(Human)
South China Agricultural University

Curated by ChEMBL
LigandPNGBDBM50502863(CHEMBL4542316)
Affinity DataIC50: 4.16E+4nMAssay Description:Inhibition of PDE4B in human PBMC assessed as inhibition in LPS-induced TNFalpha production preincubated for 30 mins followed by LPS stimulation for ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/17/2021
Entry Details Article
PubMed