BDBM50502834 CHEMBL4442543

SMILES CC(C)C[C@H](NC(=O)c1ccccc1)C(=O)NC1(CC1)C#N

InChI Key InChIKey=CIHXWBMSCJPIFY-UHFFFAOYSA-N

Data  4 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50502834   

TargetProcathepsin L(Human)
Universidade De S£O Paulo

Curated by ChEMBL
LigandPNGBDBM50502834(CHEMBL4442543)
Affinity DataKi:  20nMAssay Description:Inhibition of Cathepsin L (unknown origin) using Z-Phe-Arg-7-amido-4-methylcoumarin as substrate preincubated for 2 mins followed by susbtrate additi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/17/2021
Entry Details Article
PubMed
TargetProcathepsin L(Human)
Universidade De S£O Paulo

Curated by ChEMBL
LigandPNGBDBM50502834(CHEMBL4442543)
Affinity DataKi:  20nMAssay Description:Inhibition of human cathepsin L using Z-Phe-Arg-7-amido-4-methylcoumarin as substrate preincubated for 2 mins followed by substrate addition by fluor...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/25/2022
Entry Details Article
PubMed
TargetCruzipain(Trypanosoma cruzi)
Universidade De S£O Paulo

Curated by ChEMBL
LigandPNGBDBM50502834(CHEMBL4442543)
Affinity DataKi:  50nMAssay Description:Inhibition of Trypanosoma cruzi cruzain using Z-Phe-Arg-7-amido-4-methylcoumarin as substrate preincubated for 2 mins followed by susbtrate addition ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/17/2021
Entry Details Article
PubMed
TargetCruzipain(Trypanosoma cruzi)
Universidade De S£O Paulo

Curated by ChEMBL
LigandPNGBDBM50502834(CHEMBL4442543)
Affinity DataKi:  50nMAssay Description:Inhibition of recombinant Trypanosoma cruzi cruzain using Z-Phe-Arg-7-amido-4-methylcoumarin as substrate preincubated for 2 mins followed by substra...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/25/2022
Entry Details Article
PubMed