BDBM50502646 CHEMBL4579838

SMILES CCOc1ccc(cc1)N1C[C@@]2(CCC[C@](C)(Cn3cnc4ccc(cc34)C#N)C2)OC1=O

InChI Key InChIKey=ZFMJTMOXMDVUHG-UHFFFAOYSA-N

Data  1 IC50

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50502646   

TargetTransient receptor potential cation channel subfamily V member 4(Human)
Glaxosmithkline

Curated by ChEMBL

LigandBDBM50502646(CHEMBL4579838)Copy SMILESCopy InChI

Affinity DataIC50: 5.20nMAssay Description:Inhibition of human TRPV4 expressed in baculovirus infected HEK/MSR 2 cells pre-incubated for 10 mins followed by GSK634775A addition by Fura-2 dye b...More data for this Ligand-Target Pair

Target InfoPDB
UniProtKB/SwissProt
GoogleScholar

Ligand InfoPC cidPC sidSimilars

In Depth
Date in BDB:
2/17/2021
Entry Details Article
Copy Entry DOIPubMed
Copy Rxn URL