BDBM50502626 CHEMBL4536058

SMILES C[C@]1(Cn2cnc3ccc(cc23)C#N)CCC[C@@]2(CN(C(=O)O2)c2cnc(cn2)C2CC2)C1

InChI Key InChIKey=ZKTUOTOXMOHSDN-UHFFFAOYSA-N

Data  1 IC50

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50502626   

TargetTransient receptor potential cation channel subfamily V member 4(Human)
Glaxosmithkline

Curated by ChEMBL

LigandBDBM50502626(CHEMBL4536058)Copy SMILESCopy InChI

Affinity DataIC50: 1.5nMAssay Description:Inhibition of human TRPV4 expressed in baculovirus infected HEK/MSR 2 cells pre-incubated for 10 mins followed by GSK634775A addition by Fura-2 dye b...More data for this Ligand-Target Pair

Target InfoPDB
UniProtKB/SwissProt
GoogleScholar

Ligand InfoPC cidPC sidSimilars

In Depth
Date in BDB:
2/17/2021
Entry Details Article
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