BDBM50502587 CHEMBL4463125

SMILES CCc1nc(C)c(o1)C(=O)Nc1ccc(cc1)-c1ccc(cc1)C12CCC(CC(O)=O)(CC1)OC2

InChI Key InChIKey=WDOFVORFQCWUDU-UHFFFAOYSA-N

Data  1 IC50  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50502587   

TargetDiacylglycerol O-acyltransferase 1(Human)
Novartis Institutes For Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50502587(CHEMBL4463125)
Affinity DataIC50: 540nMAssay Description:Inhibition of recombinant human his-tagged DGAT1 expressed in Sf9 insect cells using oleoyl-CoA and diolein as substrates incubated for 30 mins by LC...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/17/2021
Entry Details Article
PubMed
TargetDiacylglycerol O-acyltransferase 1(Mouse)
Novartis Institutes For Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50502587(CHEMBL4463125)
Affinity DataEC50:  56nMAssay Description:Inhibition of DGAT1 in mouse C2C12 cells assessed as reduction in intracellular triglyceride production incubated for 2 hrs in presence of BSA-comple...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/17/2021
Entry Details Article
PubMed