BDBM50502478 CHEMBL4515689

SMILES Cn1ncc(Cl)c1-c1cc(sc1Cl)C(=O)N[C@@H]1CNCC[C@H]1c1cccc(F)c1

InChI Key InChIKey=YFPSSYQGBFIFHX-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50502478   

TargetRAC-alpha serine/threonine-protein kinase(Human)
Hangzhou Institute of Innovative Medicine

Curated by ChEMBL
LigandPNGBDBM50502478(CHEMBL4515689)
Affinity DataIC50: 102nMAssay Description:Inhibition of Akt1 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/17/2021
Entry Details Article
PubMed
TargetRAC-alpha serine/threonine-protein kinase(Human)
Hangzhou Institute of Innovative Medicine

Curated by ChEMBL
LigandPNGBDBM50502478(CHEMBL4515689)
Affinity DataIC50: 102nMAssay Description:Inhibition of human Akt1 expressed in Escherichia coli using STK Substrate 2-biotin as substrate incubated for 1 hr by HTRF assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/25/2021
Entry Details Article
PubMed