BDBM50502285 CHEMBL4543869

SMILES COc1cc2nc(nc(C#N)c2cc1-c1cnco1)C(N)CC(C)C

InChI Key InChIKey=BJGMRGWCOBKGME-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50502285   

TargetAP2-associated protein kinase 1(Human)
Ku Leuven

Curated by ChEMBL
LigandPNGBDBM50502285(CHEMBL4543869)
Affinity DataIC50: 6nMAssay Description:Inhibition of thrombin-recognition site-fused GST-tagged human AAK1 expressed in bacterial expression system using 5-FAM-Aha-KEEQSQITSQVTGQIGWR-NH2 a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/17/2021
Entry Details Article
PubMed
TargetAP2-associated protein kinase 1(Human)
Ku Leuven

Curated by ChEMBL
LigandPNGBDBM50502285(CHEMBL4543869)
Affinity DataIC50: 6.20nMAssay Description:Inhibition of recombinant human GST-Xa-tagged-AAK1 (30 to 330 residues) using (5-FAM)-Aha-KEEQSQITSQVTGQIGWR-NH2 as substrate incubated for 3 hrs in ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/25/2023
Entry Details
PubMed
TargetAP2-associated protein kinase 1(Human)
Ku Leuven

Curated by ChEMBL
LigandPNGBDBM50502285(CHEMBL4543869)
Affinity DataIC50: 6.20nMAssay Description:Inhibition of AAK1 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/14/2024
Entry Details
PubMed