BDBM50501284 CHEMBL3944697

SMILES COc1cc(c(c(c1)F)C(=O)c2ccnc(n2)Nc3ccc(cc3)C#N)F

InChI Key InChIKey=FZZMKUKEMAVUGK-UHFFFAOYSA-N

Data  2 EC50

PDB links: 1 PDB ID matches this monomer.

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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50501284   

TargetReverse transcriptase(Human immunodeficiency virus type 1)
Czech Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50501284(CHEMBL3944697)
Affinity DataEC50:  347nMAssay Description:Inhibition of HIV-1 3B reverse transcriptase K103N mutant infected in human MT4 cells assessed as inhibition of viral replication after 5 days by cel...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/4/2020
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetReverse transcriptase(Human immunodeficiency virus type 1)
Czech Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50501284(CHEMBL3944697)
Affinity DataEC50: >500nMAssay Description:Inhibition of reverse transcriptase Y181C mutant in HIV-1 3B infected in human MT4 cells assessed as inhibition of viral replication after 5 days by ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/4/2020
Entry Details Article
PubMedPDB3D3D Structure (crystal)