BDBM50500766 CHEMBL3754409

SMILES CC(C)(C)c1ccc(CN(Cc2ccccc2)C2=NCC(CI)S2)cc1

InChI Key InChIKey=RJTNIBPASYBGPL-UHFFFAOYSA-N

Data  3 KI  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50500766   

TargetLiver carboxylesterase(Pig)
Institute of Physiologically Active Compounds Russian Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50500766(CHEMBL3754409)
Affinity DataIC50: 220nMAssay Description:Inhibition of porcine liver carboxylesterase using 4-nitrophenol acetate as substrate by spectrophotometric analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/4/2020
Entry Details Article
PubMed
TargetCholinesterase(Horse)
Institute of Physiologically Active Compounds Russian Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50500766(CHEMBL3754409)
Affinity DataIC50: 770nMAssay Description:Inhibition of equine serum BChE using butyrylthiocholine iodide as substrate preincubated for 10 mins followed by substrate addition by Ellman's meth...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/4/2020
Entry Details Article
PubMed
TargetCholinesterase(Horse)
Institute of Physiologically Active Compounds Russian Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50500766(CHEMBL3754409)
Affinity DataKi:  270nMAssay Description:Competitive inhibition of equine serum BChE using butyrylthiocholine iodide as substrate assessed as steady state inhibition constant preincubated fo...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/4/2020
Entry Details Article
PubMed
TargetLiver carboxylesterase(Pig)
Institute of Physiologically Active Compounds Russian Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50500766(CHEMBL3754409)
Affinity DataKi:  400nMAssay Description:Noncompetitive inhibition of porcine liver carboxylesterase using 4-nitrophenol acetate as substrate assessed as steady state inhibition constant pre...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/4/2020
Entry Details Article
PubMed
TargetCholinesterase(Horse)
Institute of Physiologically Active Compounds Russian Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50500766(CHEMBL3754409)
Affinity DataKi:  1.20E+3nMAssay Description:Noncompetitive inhibition of equine serum BChE using butyrylthiocholine iodide as substrate assessed as steady state inhibition constant preincubated...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/4/2020
Entry Details Article
PubMed