BDBM50500593 CHEMBL4299454

SMILES [H][C@@]12CCCN1C(=O)[C@H](Cc1c[nH]c3ccccc13)NC(=O)[C@H](CC(=O)NCCCC[C@H](NC(=O)[C@@H](Cc1c[nH]c3ccccc13)NC(=O)[C@@H](CCCNC(N)=N)NC(=O)[C@@H](Cc1ccccc1)NC2=O)C(N)=O)NC(=O)[C@@H](CCCC)NC(C)=O

InChI Key InChIKey=OBWYPRDXHGPHFY-UHFFFAOYSA-N

Data  4 IC50  4 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 8 hits for monomerid = 50500593   

TargetMelanocyte-stimulating hormone receptor(Human)
University of Naples Federico II

Curated by ChEMBL
LigandPNGBDBM50500593(CHEMBL4299454)
Affinity DataIC50: 5.00E+3nMAssay Description:Displacement of 125I-labeled [Nle4,DPhe7]-alpha-MSH from human melanocortin 1 receptor expressed in HEK293 cells incubated for 40 mins by gamma count...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/4/2020
Entry Details Article
PubMed
TargetMelanocortin receptor 5(Human)
University of Naples Federico II

Curated by ChEMBL
LigandPNGBDBM50500593(CHEMBL4299454)
Affinity DataIC50: 1.00E+3nMAssay Description:Displacement of 125I-labeled [Nle4,DPhe7]-alpha-MSH from human melanocortin 5 receptor expressed in HEK293 cells incubated for 40 mins by gamma count...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/4/2020
Entry Details Article
PubMed
TargetMelanocyte-stimulating hormone receptor(Human)
University of Naples Federico II

Curated by ChEMBL
LigandPNGBDBM50500593(CHEMBL4299454)
Affinity DataEC50:  26nMAssay Description:Agonist activity at human melanocortin 1 receptor expressed in HEK293 cells assessed as intracellular cAMP accumulation incubated for 3 mins in prese...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/4/2020
Entry Details Article
PubMed
TargetMelanocortin receptor 3(Human)
University of Naples Federico II

Curated by ChEMBL
LigandPNGBDBM50500593(CHEMBL4299454)
Affinity DataEC50: >1.00E+3nMAssay Description:Agonist activity at human melanocortin 3 receptor expressed in HEK293 cells assessed as intracellular cAMP accumulation incubated for 3 mins in prese...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/4/2020
Entry Details Article
PubMed
TargetMelanocortin receptor 5(Human)
University of Naples Federico II

Curated by ChEMBL
LigandPNGBDBM50500593(CHEMBL4299454)
Affinity DataEC50:  73nMAssay Description:Agonist activity at human melanocortin 5 receptor expressed in HEK293 cells assessed as intracellular cAMP accumulation incubated for 3 mins in prese...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/4/2020
Entry Details Article
PubMed
TargetMelanocortin receptor 4(Human)
University of Naples Federico II

Curated by ChEMBL
LigandPNGBDBM50500593(CHEMBL4299454)
Affinity DataEC50:  220nMAssay Description:Agonist activity at human melanocortin 4 receptor expressed in HEK293 cells assessed as intracellular cAMP accumulation incubated for 3 mins in prese...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/4/2020
Entry Details Article
PubMed
TargetMelanocortin receptor 3(Human)
University of Naples Federico II

Curated by ChEMBL
LigandPNGBDBM50500593(CHEMBL4299454)
Affinity DataIC50: 580nMAssay Description:Displacement of 125I-labeled [Nle4,DPhe7]-alpha-MSH from human melanocortin 3 receptor expressed in HEK293 cells incubated for 40 mins by gamma count...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/4/2020
Entry Details Article
PubMed
TargetMelanocortin receptor 4(Human)
University of Naples Federico II

Curated by ChEMBL
LigandPNGBDBM50500593(CHEMBL4299454)
Affinity DataIC50: 1.00E+3nMAssay Description:Displacement of 125I-labeled [Nle4,DPhe7]-alpha-MSH from human melanocortin 4 receptor expressed in HEK293 cells incubated for 40 mins by gamma count...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/4/2020
Entry Details Article
PubMed