BDBM50500141 CHEMBL3746997

SMILES O=C(Cc1ccccc1)Nc1ccc(CCOc2ccccc2-c2cnc[nH]2)cc1

InChI Key InChIKey=UGJSPCDPWVQJIE-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50500141   

TargetIndoleamine 2,3-dioxygenase 1(Human)
Panjab University

Curated by ChEMBL
LigandPNGBDBM50500141(CHEMBL3746997)
Affinity DataIC50: 1.00E+3nMAssay Description:Inhibition of IDO1 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/20/2024
Entry Details
PubMed
TargetIndoleamine 2,3-dioxygenase 1(Human)
Panjab University

Curated by ChEMBL
LigandPNGBDBM50500141(CHEMBL3746997)
Affinity DataIC50: 1.00E+3nMAssay Description:Inhibition of C-terminal 6His-tagged human IDO using L-tryptophan as substrate preincubated for 5 mins followed by substrate addition measured after ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/4/2020
Entry Details Article
PubMed
TargetIndoleamine 2,3-dioxygenase 1(Human)
Panjab University

Curated by ChEMBL
LigandPNGBDBM50500141(CHEMBL3746997)
Affinity DataIC50: 28nMAssay Description:Inhibition of human IDO1 using L-tryptophan as substrate assessed as reduction in N-formyl kynurenine formation by UV-visible spectroscopic analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/22/2024
Entry Details
PubMed