BDBM50500089 CHEMBL3740910

SMILES FC(F)(F)c1cccc(Nc2ncnc3ccc(NC(=O)Nc4ccc(CN5CCCC5)cc4)cc23)c1

InChI Key InChIKey=NLSNSCBPWXRRPL-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50500089   

TargetVascular endothelial growth factor receptor 2(Human)
Xi'An Jiaotong University

Curated by ChEMBL
LigandPNGBDBM50500089(CHEMBL3740910)
Affinity DataIC50: 565nMAssay Description:Inhibition of VEGFR-2 (unknown origin) assessed as ATP level by luminescence analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/4/2020
Entry Details Article
PubMed
TargetEpidermal growth factor receptor(Human)
Xi'An Jiaotong University

Curated by ChEMBL
LigandPNGBDBM50500089(CHEMBL3740910)
Affinity DataIC50: 4.10nMAssay Description:Inhibition of wild-type EGFR tyrosine kinase (unknown origin) assessed as ATP level by luminescence analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/4/2020
Entry Details Article
PubMed
TargetEpidermal growth factor receptor(Human)
Xi'An Jiaotong University

Curated by ChEMBL
LigandPNGBDBM50500089(CHEMBL3740910)
Affinity DataIC50: 12nMAssay Description:Inhibition of EGFR tyrosine kinase L858R mutant (unknown origin) assessed as ATP level by luminescence analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/4/2020
Entry Details Article
PubMed