BDBM50500088 CHEMBL3740144

SMILES CN1CCN(Cc2ccc(NC(=O)Nc3ccc4ncnc(Nc5ccc(OCc6cccc(F)c6)c(Cl)c5)c4c3)cc2)CC1

InChI Key InChIKey=VBIIJIMQUUULLK-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50500088   

TargetEpidermal growth factor receptor(Human)
Xi'An Jiaotong University

Curated by ChEMBL
LigandPNGBDBM50500088(CHEMBL3740144)
Affinity DataIC50: 8.40nMAssay Description:Inhibition of wild-type EGFR tyrosine kinase (unknown origin) assessed as ATP level by luminescence analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/4/2020
Entry Details Article
PubMed
TargetVascular endothelial growth factor receptor 2(Human)
Xi'An Jiaotong University

Curated by ChEMBL
LigandPNGBDBM50500088(CHEMBL3740144)
Affinity DataIC50: 1.00E+3nMAssay Description:Inhibition of VEGFR-2 (unknown origin) assessed as ATP level by luminescence analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/4/2020
Entry Details Article
PubMed