BDBM50499867 CHEMBL3740041

SMILES CCCN(CCN1CCN(CC1)c1ccc2cc[nH]c2c1Cl)[C@H]1CCc2nc(N)sc2C1

InChI Key InChIKey=IQOHRYVJGPXDMK-UHFFFAOYSA-N

Data  2 KI  2 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50499867   

TargetD(2) dopamine receptor(Human)
Wayne State University

Curated by ChEMBL
LigandPNGBDBM50499867(CHEMBL3740041)
Affinity DataEC50:  3.20nMAssay Description:Agonist activity at human D2 receptor expressed in CHO cells by [35S]GTPgammaS binding assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/4/2020
Entry Details Article
PubMed
TargetD(3) dopamine receptor(Human)
Wayne State University

Curated by ChEMBL
LigandPNGBDBM50499867(CHEMBL3740041)
Affinity DataEC50:  1.40nMAssay Description:Agonist activity at human D3 receptor expressed in CHO cells by [35S]GTPgammaS binding assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/4/2020
Entry Details Article
PubMed
TargetD(3) dopamine receptor(Rat)
Wayne State University

Curated by ChEMBL
LigandPNGBDBM50499867(CHEMBL3740041)
Affinity DataKi:  1.20nMAssay Description:Displacement of [3H]Spiroperidol from cloned rat dopamine D3 receptor expressed in HEK293 cells by liquid scintillation counting analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/4/2020
Entry Details Article
PubMed
TargetD(2) dopamine receptor(Rat)
Wayne State University

Curated by ChEMBL
LigandPNGBDBM50499867(CHEMBL3740041)
Affinity DataKi:  16nMAssay Description:Displacement of [3H]Spiroperidol from cloned rat dopamine D2L receptor expressed in HEK293 cells by liquid scintillation counting analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/4/2020
Entry Details Article
PubMed