BDBM50499725 CHEMBL3740963

SMILES Brc1ccccc1C(=O)c1ccc(OCC(=O)Nc2cccnc2)cc1

InChI Key InChIKey=QNWXOXKHLFTJBA-UHFFFAOYSA-N

Data  1 IC50  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50499725   

Target1,3-beta-glucan synthase component GSC2(Baker's yeast)
Leiden University

Curated by ChEMBL
LigandPNGBDBM50499725(CHEMBL3740963)
Affinity DataEC50:  1.20E+4nMAssay Description:Induction of dissociation of [3H]-dofetilide from Kv11.1 channel (unknown origin) assessed as dissociation rate expressed in HEK293 cells after 1 hrMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/4/2020
Entry Details Article
PubMed
TargetPotassium voltage-gated channel subfamily H member 2(Human)
Leiden University

Curated by ChEMBL
LigandPNGBDBM50499725(CHEMBL3740963)
Affinity DataIC50: 36nMAssay Description:Displacement of [3H]dofetilide from human ERG stably expressed in HEK293 cell membranes assessed as unlabelled dofetilide IC50 at 10 uM measured afte...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/29/2022
Entry Details Article
PubMed