BDBM50499721 CHEMBL3739748

SMILES [H][C@@]12C[C@]34C[C@@H](C)CN3C[C@@]1(C[C@@]1(C(=O)Nc3c1ccc1OC(C)(C)C=COc31)C2(C)C)N(C)C4=O

InChI Key

Data  1 IC50  2 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50499721   

TargetAmyloid-beta precursor protein(Human)
Korea University

Curated by ChEMBL
LigandPNGBDBM50499721(CHEMBL3739748)
Affinity DataEC50: >3.00E+5nMAssay Description:Inhibition of amyloid beta (25 to 35 residues) (unknown origin) aggregate-induced toxicity in rat PC12 cells preincubated for 1 hr followed by amyloi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/4/2020
Entry Details Article
PubMed
TargetAmyloid-beta precursor protein(Human)
Korea University

Curated by ChEMBL
LigandPNGBDBM50499721(CHEMBL3739748)
Affinity DataIC50: 2.70E+5nMAssay Description:Inhibition of amyloid beta (1 to 42 residues) (unknown origin) aggregation after 24 hrs by thioflavin T assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/4/2020
Entry Details Article
PubMed
TargetAmyloid-beta precursor protein(Human)
Korea University

Curated by ChEMBL
LigandPNGBDBM50499721(CHEMBL3739748)
Affinity DataEC50:  1.05E+5nMAssay Description:Inhibition of amyloid beta (1 to 42 residues) (unknown origin) aggregate-induced toxicity in rat PC12 cells assessed as cell viability at 4 to 100 ug...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/4/2020
Entry Details Article
PubMed