BDBM50499717 CHEMBL3739499

SMILES [H][C@]12CC=C(C)[C@@]3(Cc4c(O3)c(C)c(C)oc4=O)[C@]1(C)CC[C@]1([H])[C@]2(C)C=CC(=O)OC1(C)C

InChI Key InChIKey=FJGNDLFUTLJNOP-UHFFFAOYSA-N

Data  1 IC50  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50499717   

TargetAmyloid-beta precursor protein(Human)
Korea University

Curated by ChEMBL
LigandPNGBDBM50499717(CHEMBL3739499)
Affinity DataEC50:  6.54E+4nMAssay Description:Inhibition of amyloid beta (25 to 35 residues) (unknown origin) aggregate-induced toxicity in rat PC12 cells preincubated for 1 hr followed by amyloi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/4/2020
Entry Details Article
PubMed
TargetAmyloid-beta precursor protein(Human)
Korea University

Curated by ChEMBL
LigandPNGBDBM50499717(CHEMBL3739499)
Affinity DataIC50: 3.00E+5nMAssay Description:Inhibition of amyloid beta (1 to 42 residues) (unknown origin) aggregation after 24 hrs by thioflavin T assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/4/2020
Entry Details Article
PubMed