BDBM50499197 CHEMBL3736465

SMILES OCCc1ccc(cc1)-n1c(NC(=O)c2cccc(c2)C(F)(F)F)nc2cc(CN3CCCCC3)ccc12

InChI Key InChIKey=DQEKCEBMQCYICP-UHFFFAOYSA-N

Data  3 KI

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50499197   

TargetInterleukin-1 receptor-associated kinase 4(Human)
Amgen

Curated by ChEMBL

LigandBDBM50499197(CHEMBL3736465)Copy SMILESCopy InChI

Affinity DataKi:  1.30nMAssay Description:Inhibition of recombinant full length IRAK-4 (unknown origin) using the biotinylated substrate RRRVTSPARRS by chemiluminescent ELISAMore data for this Ligand-Target Pair

Target InfoPDBKEGG
UniProtKB/SwissProt
GoogleScholar

Ligand InfoPC cidPC sidSimilars

In Depth
Date in BDB:
9/4/2020
Entry Details Article
Copy Entry DOIPubMed
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TargetInterleukin-1 receptor-associated kinase 1(Human)
Amgen

Curated by ChEMBL

LigandBDBM50499197(CHEMBL3736465)Copy SMILESCopy InChI

Affinity DataKi:  12nMAssay Description:Inhibition of IRAK-1 (unknown origin)More data for this Ligand-Target Pair

Target InfoPDBKEGG
UniProtKB/SwissProt
GoogleScholar

Ligand InfoPC cidPC sidSimilars

In Depth
Date in BDB:
9/4/2020
Entry Details Article
Copy Entry DOIPubMed
Copy Rxn URL

TargetMitogen-activated protein kinase kinase kinase 7(Human)
Amgen

Curated by ChEMBL

LigandBDBM50499197(CHEMBL3736465)Copy SMILESCopy InChI

Affinity DataKi:  700nMAssay Description:Inhibition of TAK1 (unknown origin)More data for this Ligand-Target Pair

Target InfoPDBKEGG
UniProtKB/SwissProt
GoogleScholar

Ligand InfoPC cidPC sidSimilars

In Depth
Date in BDB:
9/4/2020
Entry Details Article
Copy Entry DOIPubMed
Copy Rxn URL