BDBM50499196 CHEMBL3735448

SMILES CC(C)(C)C(=O)Oc1ccc2n(c(NC(=O)c3cccc(c3)[N+]([O-])=O)nc2c1)-c1ccc(CCCO)cc1

InChI Key InChIKey=RGJUJSDOHVLJHD-UHFFFAOYSA-N

Data  2 IC50

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50499196   

TargetInterleukin-1 receptor-associated kinase 4(Human)
Amgen

Curated by ChEMBL

LigandBDBM50499196(CHEMBL3735448)Copy SMILESCopy InChI

Affinity DataIC50: 150nMAssay Description:Inhibition of recombinant full length IRAK-4 (unknown origin) using the biotinylated substrate RRRVTSPARRS by chemiluminescent ELISAMore data for this Ligand-Target Pair

Target InfoPDBKEGG
UniProtKB/SwissProt
GoogleScholar

Ligand InfoPC cidPC sidSimilars

In Depth
Date in BDB:
9/4/2020
Entry Details Article
Copy Entry DOIPubMed
Copy Rxn URL

TargetInterleukin-1 receptor-associated kinase 1(Human)
Amgen

Curated by ChEMBL

LigandBDBM50499196(CHEMBL3735448)Copy SMILESCopy InChI

Affinity DataIC50: 900nMAssay Description:Inhibition of IRAK-1 (unknown origin)More data for this Ligand-Target Pair

Target InfoPDBKEGG
UniProtKB/SwissProt
GoogleScholar

Ligand InfoPC cidPC sidSimilars

In Depth
Date in BDB:
9/4/2020
Entry Details Article
Copy Entry DOIPubMed
Copy Rxn URL