BDBM50499133 CHEMBL3735836

SMILES COc1cccc(c1)-c1nc2ccc(nn2c1-c1ccncc1)N1CCN(C)CC1

InChI Key InChIKey=PGJNVECBMPJQRU-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50499133   

TargetCyclin-dependent kinase 5 activator 1(Human)
University of Tours

Curated by ChEMBL
LigandPNGBDBM50499133(CHEMBL3735836)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of human recombinant CDK5/P25 expressed in Escherichia coli using histone H1 substrate after 30 mins by scintillation and luminescence cou...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/4/2020
Entry Details Article
PubMed
TargetSerine/threonine-protein kinase haspin(Human)
University of Tours

Curated by ChEMBL
LigandPNGBDBM50499133(CHEMBL3735836)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of human recombinant haspin kinase domain expressed in Escherichia coli BL21-KRX using histone H3 (1 to 21) peptide substrate after 30 min...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/4/2020
Entry Details Article
PubMed
TargetGlycogen synthase kinase-3 beta/[Tau protein] kinase(Pig)
University of Tours

Curated by ChEMBL
LigandPNGBDBM50499133(CHEMBL3735836)
Affinity DataIC50: 8.80E+3nMAssay Description:Inhibition of porcine brain GSK-3 alpha/beta using GS-1 substrate after 30 mins by scintillation and luminescence counting method in the presence of ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/4/2020
Entry Details Article
PubMed