BDBM50499081 CHEMBL3735916

SMILES Cc1ccc(cc1I)C(=O)N1CCN(CC1)C(=O)c1cc(Cc2n[nH]c(=O)c3ccccc23)ccc1F

InChI Key InChIKey=UEXLZKRRXDGMSC-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50499081   

TargetPoly [ADP-ribose] polymerase 1(Human)
University of Glasgow

Curated by ChEMBL
LigandPNGBDBM50499081(CHEMBL3735916)
Affinity DataIC50: 17nMAssay Description:Inhibition of PARP1 (unknown origin) incubated for 10 mins using biotinylated NAD+ and activated DNA by colorimetric assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/4/2020
Entry Details Article
PubMed