BDBM50499075 CHEMBL3735832

SMILES Fc1ccc(Cc2n[nH]c(=O)c3ccccc23)cc1C(=O)N1CCN(CC1)C(=O)Cc1cccc(I)c1

InChI Key InChIKey=JSLHOUUNORIRKI-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50499075   

TargetPoly [ADP-ribose] polymerase 1(Human)
University of Glasgow

Curated by ChEMBL
LigandPNGBDBM50499075(CHEMBL3735832)
Affinity DataIC50: 5.80nMAssay Description:Inhibition of PARP1 (unknown origin) incubated for 10 mins using biotinylated NAD+ and activated DNA by colorimetric assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/4/2020
Entry Details Article
PubMed