BDBM50498905 CHEMBL3736012

SMILES Cc1cccc2c1c1COC(Cc1[nH]c2=O)C(C)(C)CO

InChI Key InChIKey=JZXQZQOGBFSTTQ-UHFFFAOYSA-N

Data  2 IC50  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50498905   

TargetPoly [ADP-ribose] polymerase tankyrase-1/tankyrase-2(Human)
Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM50498905(CHEMBL3736012)
Affinity DataEC50:  7nMAssay Description:Inhibition of Tankyrase in human DLD1 cells assessed as T-cell factor level after 24 hrs by luciferase reporter gene assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/4/2020
Entry Details Article
PubMed
TargetPoly [ADP-ribose] polymerase tankyrase-2(Human)
Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM50498905(CHEMBL3736012)
Affinity DataIC50: 60nMAssay Description:Inhibition of TNKS2 (unknown origin) by fluorescence analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/4/2020
Entry Details Article
PubMed
TargetPoly [ADP-ribose] polymerase tankyrase-2(Human)
Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM50498905(CHEMBL3736012)
Affinity DataIC50: 60nMAssay Description:Inhibition of human recombinant TNKS2More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/18/2024
Entry Details
PubMed