BDBM50498615 CHEMBL3609651

SMILES CC(=O)NCCCC[C@H](NC(=O)[C@H](CCCCNC(C)=S)NC(=O)[C@H](Cc1ccc2ccccc2c1)NC(C)=O)C(N)=O

InChI Key InChIKey=OUJMTYSEKPPLQM-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50498615   

TargetNAD-dependent protein deacetylase sirtuin-1(Human)
Jiangsu University

Curated by ChEMBL
LigandPNGBDBM50498615(CHEMBL3609651)
Affinity DataIC50: 1.26E+4nMAssay Description:Inhibition of human His6 or GST-tagged SIRT1 after 10 mins by Dixon plot analysis in presence of beta-NADMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/3/2020
Entry Details Article
PubMed
TargetNAD-dependent protein deacetylase sirtuin-2(Human)
Jiangsu University

Curated by ChEMBL
LigandPNGBDBM50498615(CHEMBL3609651)
Affinity DataIC50: 1.20E+4nMAssay Description:Inhibition of human His6-tagged SIRT2 after 12 mins by Dixon plot analysis in presence of beta-NADMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/3/2020
Entry Details Article
PubMed
LigandPNGBDBM50498615(CHEMBL3609651)
Affinity DataIC50: 1.29E+3nMAssay Description:Inhibition of human His6-tagged SIRT3 after 10 mins by Dixon plot analysis in presence of beta-NADMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/3/2020
Entry Details Article
PubMed