BDBM50498473 CHEMBL1230654

SMILES CCC[C@H](C(O)=O)c1c(C)nc2ccc(Cl)cc2c1-c1ccccc1

InChI Key InChIKey=XRPUJSGGRFQZPJ-UHFFFAOYSA-N

Data  3 IC50  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50498473   

TargetIntegrase(Human immunodeficiency virus type 1)
University of Siena

Curated by ChEMBL
LigandPNGBDBM50498473(CHEMBL1230654)
Affinity DataIC50: 2.00E+4nMAssay Description:Inhibition of His-tagged HIV-1 integrase-mediated 3' processing and strand transfer reactions using 5'-ACAGGCCTAGCACGCGTCG-Biotin-3' annealed with 5'...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/3/2020
Entry Details Article
PubMed
TargetIntegrase(Human immunodeficiency virus type 1)
University of Siena

Curated by ChEMBL
LigandPNGBDBM50498473(CHEMBL1230654)
Affinity DataIC50: 2.35E+3nMAssay Description:Binding affinity to recombinant HIV-1 integrase catalytic core domain expressed in Escherichia coli assessed as inhibition of interaction with LEDFG/...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/3/2020
Entry Details Article
PubMed
TargetIntegrase(Human immunodeficiency virus type 1)
University of Siena

Curated by ChEMBL
LigandPNGBDBM50498473(CHEMBL1230654)
Affinity DataIC50: 6.00E+3nMAssay Description:Inhibition of His-tagged HIV-1 integrase-mediated 3' processing and strand transfer reactions using 5'-ACAGGCCTAGCACGCGTCG-Biotin-3' annealed with 5'...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/3/2020
Entry Details Article
PubMed
TargetIntegrase(Human immunodeficiency virus type 1)
University of Siena

Curated by ChEMBL
LigandPNGBDBM50498473(CHEMBL1230654)
Affinity DataEC50:  69nMAssay Description:Antiviral activity against HIV1 assessed as inhibition of integraseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/4/2020
Entry Details Article
PubMed