BDBM50498452 CHEMBL3596873

SMILES CC(C)(C)c1cc(NC(=O)Nc2cccc(Oc3cncc(n3)-c3ccc(cc3)S(C)(=O)=O)c2)no1

InChI Key InChIKey=MAGVRNDWTTZRHB-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50498452   

TargetEphrin type-B receptor 2(Human)
The University of Arizona

Curated by ChEMBL
LigandPNGBDBM50498452(CHEMBL3596873)
Affinity DataIC50: 2.00E+3nMAssay Description:Inhibition of EphB2 (unknown origin) using ATP and 5FAM tagged TrkA peptide substrate incubated for 60 mins by microfluidics assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/3/2020
Entry Details Article
PubMed
TargetVascular endothelial growth factor receptor 2(Human)
The University of Arizona

Curated by ChEMBL
LigandPNGBDBM50498452(CHEMBL3596873)
Affinity DataIC50: 4.80E+3nMAssay Description:Inhibition of KDR (unknown origin) using ATP and 5FAM tagged TrkA peptide substrate incubated for 60 mins by microfluidics assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/3/2020
Entry Details Article
PubMed
TargetHigh affinity nerve growth factor receptor(Human)
The University of Arizona

Curated by ChEMBL
LigandPNGBDBM50498452(CHEMBL3596873)
Affinity DataIC50: 92nMAssay Description:Inhibition of human recombinant TrkA using ATP and 5FAM tagged TrkA peptide substrate incubated for 60 mins by microfluidics assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/3/2020
Entry Details Article
PubMed
TargetProto-oncogene tyrosine-protein kinase receptor Ret(Human)
The University of Arizona

Curated by ChEMBL
LigandPNGBDBM50498452(CHEMBL3596873)
Affinity DataIC50: 210nMAssay Description:Inhibition of RET (unknown origin) using ATP and 5FAM tagged TrkA peptide substrate incubated for 60 mins by microfluidics assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/3/2020
Entry Details Article
PubMed