BDBM50498229 CHEMBL3577575

SMILES CC(C)CN(C[C@H]([C@H](Cc1ccccc1)NC(=O)O[C@H]2CO[C@@H]3[C@H]2C(CO3)(F)F)O)S(=O)(=O)c4ccc(cc4)N

InChI Key InChIKey=UQYAKJSDOQPRAX-UHFFFAOYSA-N

Data  2 KI  1 IC50

PDB links: 3 PDB IDs match this monomer.

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50498229   

TargetProtease(Human immunodeficiency virus type 1)
Georgia State University

Curated by ChEMBL
LigandPNGBDBM50498229(CHEMBL3577575)
Affinity DataIC50: 1.00E+3nMAssay Description:Inhibition of N-terminal autoprocessing of transframe region-comprising wild type HIV1 protease precursor by SDS-PAGE methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/3/2020
Entry Details Article
PubMed
TargetGag-Pol polyprotein [489-587](Human immunodeficiency virus type 1)
Purdue University

Curated by ChEMBL
LigandPNGBDBM50498229(CHEMBL3577575)
Affinity DataKi:  0.00580nMAssay Description:Binding affinity to HIV1 protease assessed as inhibition constantMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/22/2024
Entry Details
PubMed
TargetProtease(Human immunodeficiency virus type 1)
Georgia State University

Curated by ChEMBL
LigandPNGBDBM50498229(CHEMBL3577575)
Affinity DataKi:  0.00600nMAssay Description:Inhibition of wild type HIV1 proteaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/3/2020
Entry Details Article
PubMed