BDBM50498204 CHEMBL3421644

SMILES COc1ccc2NC(=O)\C(=C3/Nc4cc(F)c(F)cc4/C/3=N\OCCO)c2c1

InChI Key InChIKey=RGSOPECOGHDZOA-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50498204   

TargetCyclin-T1/Cyclin-dependent kinase 9(Human)
Peking Union Medical College

Curated by ChEMBL
LigandPNGBDBM50498204(CHEMBL3421644)
Affinity DataIC50: 300nMAssay Description:Inhibition of against CDK9/cyclinT1 (unknown origin) using Ulight-CFFKNIVTPRTPPPSQGK-amide substrate and ATP incubated for 90 mins by fluorescence ba...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/3/2020
Entry Details Article
PubMed
TargetCyclin-dependent kinase 2/G1/S-specific cyclin-E1(Human)
Peking Union Medical College

Curated by ChEMBL
LigandPNGBDBM50498204(CHEMBL3421644)
Affinity DataIC50: 400nMAssay Description:Inhibition of against CDK2/cyclinE1 (unknown origin) using Ulight-CFFKNIVTPRTPPPSQGK-amide substrate and ATP incubated for 15 mins by fluorescence ba...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/3/2020
Entry Details Article
PubMed