BDBM50498200 CHEMBL3187395

SMILES Clc1ccc2[nH]nnc2c1

InChI Key InChIKey=PZBQVZFITSVHAW-UHFFFAOYSA-N

Data  1 KI  1 Kd

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50498200   

TargetDual specificity tyrosine-phosphorylation-regulated kinase 1A(Human)
Eberhard Karls Universit£T T£Bingen

Curated by ChEMBL
LigandPNGBDBM50498200(CHEMBL3187395)
Affinity DataKd:  8.00E+4nMAssay Description:Binding affinity to human DYRK1A (127 to 485 residues) expressed in Escherichia coli BL21 (DE3) cells assessed as dissociation constant by isothermal...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/20/2023
Entry Details
PubMed
TargetCoagulation factor VII/Tissue factor(Human)
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50498200(CHEMBL3187395)
Affinity DataKi:  8.70E+6nMAssay Description:Inhibition of human soluble tissue factor/factor VIIa expressed in Origami B (DE3) using D-Ile-Pro-Arg-pNA as substrate after 30 mins by spectrophoto...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/3/2020
Entry Details Article
PubMed